Insights
Featured Articles
Information is the Root of Morale
June 6, 2026
Morale is emotional, but the conditions that create morale are often informational. This article explores how non-credible milestones, swirl, undefined success, broken feedback loops, and constant reprioritization erode confidence – and why information is often the true root of morale.
Why Retrofitting Fermentation Infrastructure Is Harder Than It Looks
May 30, 2026
Industrial biotech has repeatedly explored repurposing existing fermentation infrastructure rather than rebuilding capacity from scratch. But adapting facilities designed for one process to another is often far more complicated than early models assume. This piece explores the economic, operational, and manufacturing realities that make scaling biology one of industrial biotech’s hardest problems.
I’d Switch to Alternative Meat Tomorrow. Here’s What Still Has to Change
February 5, 2026
I’d switch to alternative meat tomorrow – if it were more available, affordable, and tasted good.
That qualifier turns out to matter more than most debates acknowledge.
Your High Throughput Screen Isn’t Broken
January 9, 2026
After more than 20 years building and troubleshooting high-throughput screens, one lesson has consistently held true: “You always get what you screen for.” This piece explores how assay conditions shape the biology that emerges from a screen, why promising hits often fail downstream, and how hidden assumptions in assay design can distort what teams think they are measuring.
Featured Series
Organizations rarely fail all at once. More often, they drift gradually – through misalignment, hidden constraints, delayed feedback, and decisions that make sense locally but compound system-wide over time.
Navigation & Drift explores leadership, execution, and strategy in complex adaptive systems through the language of seamanship, command, and navigation.